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Oxygen Therapy May Slow the Hallmarks of Alzheimer’s According to New Study


Tel aviv university

A team of researchers has managed to restore brain trauma using hyperbaric oxygen therapy.

This is the first time in the scientific world that non-drug therapy has been shown to be effective in preventing the core biological processes responsible for the development of Alzheimer’s disease.

Using a specific hyperbaric oxygen therapy (HBOT) protocol, cerebral blood flow (CBF) improved / increased in elderly patients by 16-23%, alleviating vascular dysfunction and amyloid load.

The Tel Aviv University study, part of a comprehensive research program targeting aging and the ailments that accompany it as a reversible disease, shows promise for a new strategic approach to Alzheimer’s disease prevention by addressing not just the symptoms or target biomarkers, but rather the core. pathology and biology responsible for the development of the disease.

Hyperbaric medicine is a form of therapy that requires patients to stay in special chambers in which the atmospheric pressure is much higher than that normally experienced at sea level.

In addition, they breathe air made up of 100% oxygen.

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Hyperbaric medicine is considered safe and already works to treat an extensive list of medical conditions. In recent years, scientific evidence has indicated that unique hyperbaric therapy protocols are capable of inducing repair of damaged brain tissue and renewed growth of blood vessels and nerve cells in the brain.

The first stage of the study, published in Aging journal, was carried out in an animal model, in the course of which it was conclusively demonstrated by examining brain tissues that a certain therapeutic protocol produces an improvement in vascular function and the creation of new blood vessels.

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It also prevents the deposit of new amyloid plaques in brain cells and even leads to the removal of existing amyloid plaque deposits. Amyloids are insoluble proteins. Deposits of these proteins in the brain are linked to serious degenerative conditions such as Alzheimer’s disease.

In the next stage, the effects of treatment in people over 65 with cognitive impairment were examined, with an emphasis on memory loss, a stage before Alzheimer’s and dementia.

The therapy included a series of 60 single sessions of HBOT in pressure chambers over a period of 90 days.

Effects on the brain were assessed by high resolution perfusion MRI. The hyperbaric treatment protocol resulted in: increased blood flow in the range of 16% -23%; significant improvement in memory by 16.5% on average, significant improvement in attention and information processing speed.

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Dr Ronit Shapira said: “The combination of an animal model from which we could learn the pathology of the disease, together with existing and available therapy, raises the hope that we will now be able to fight one of the greatest challenges for human beings. Westerners. world.

“Based on our findings, hyperbaric therapy given at an early age is likely to completely prevent this serious disease.”

Source: TEL-AVIV UNIVERSITY

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